Following the wanton destruction in Italy of vast numbers of Hebrew texts - especially Talmud volumes - the Basle humanist-printer Ambrosius Froben (grandson of Johannes Froben) was moved to issue a new edition of the Talmud to compensate for the losses experienced by the learned Jews of Italy. Due to Church-related censorship matters, not all Tractates were issued and so the set remained incomplete.
See R. N. N. Rabinowitz, Ma’amar al Hadpassath HaTalmud pp. 74-79; M. J. Heller, Printing the Talmud (1992) pp. 241-65.